The BNS has awarded more than £300,000 in research and travel grants over the past 10 years.
More than a 100 individuals have received grants over this period.
Last year, 15 research applications were awarded in total.
This included 8 small research grants and 5 travel grants.
Small research grants totalled £37,275 in value this year.
Generous funding from the BNS enabled Irina Vazquez-Villasenor to investigate “Neuronal Senescence as a Contributor to Neurodegeneration in Motor Neurone Disease”. This study aimed to determine whether a persistent DNA damage response and senescence pathway activation are features of motor neurone disease (MND).
Irina presented her research at the BNS meeting in 2016 and was awarded a prize for her poster. A manuscript of this work is currently under review in NAN.
|Vinton Cheng/ Azzam Ismail||Leeds||Histological and molecular characterisation of the hypoxic and inflammatory microenvironment at the brain tumour margin||£5,000|
|Sarah Howard/ Jessica Teeling||Southampton||Investigating the role of neuroinflammation on the accumulation and spread of tau pathology||£3,903|
|Alexander J Matthews/ Kathryn Urankar||Bristol||Investigating an Immunohistochemical Surrogate Marker Me3″ to Distinguish Oligodendrogliomas from Astrocytomas”||£5,000|
|Alex Waldman/ Gabriele De Luca||Oxford||Biomarkers and molecular mediators of neurodegeneration in multiple sclerosis||£5,000|
|Zeinab Abdi/ Tammaryn Lashley||UCL||Posterior cortical atrophy; a pathological characterisation||£5,000|
|Mayen Briggs/ A Lakatos||Cambridge||Human tissue validation of astrocyte phenotypes and pathological states relevant to ALS pathogenesis||£5,000|
|Annelies Quaegebeur||Oxford||Characterisation of microglial activation and synapse loss in progressive supranuclear palsy||£4,956.84|
|Alexander Bampton/ Rina Bandopadhyay||UCL||Using in situ hybridisation to detect and visualise novel cryptic exons and to delineate the spatial relationship between cryptic exons and dementia pathologies||£4,952|
|James Minshull/ A Robinson||Manchester||APOE genotyping from formalin fixed and paraffin-embedded tissue – Maximising the use of donated human brain tissue||£4,802.30|
|Rina Bandopadhyay||UCL||n.a.||Investigation of the pathological significance of vesicular dysfunction in Parkinson’s disease||£5,000|
|Rachel Ann Kline||Edinburgh||Thomas Wishart||Investigating therapy-driven changes in cell populations at spatial resolution in glioblastoma brain tumours||£5,000|
|Shoaib Ali Ajaib||Leeds||Lucy Stead||Investigating therapy-driven changes in cell populations at spatial resolution in glioblastoma brain tumours||£4,800|
|Carmine Antonio Donofrio||Manchester||Federico Roncaroli||Pathological and molecular stratification of ACTH-secreting pituitary tumours to predict recurrence after bilateral adrenalectomy||£4,595|
|Lara Marrone||Sheffield||Mimoun Azzouz||Identification of compounds reversing lysosomal pathology in Hereditary Spastic Paraplegia type 15||£5,000|
|Devina Patel||UCL||Rahul Phadke||Developing a multiplex in situ hybridisation assay||£5,000|
|Conceicao Bettencourt||UCL||Janice Holton||Parkinsonian epigenetic networks (PARKepiNets)||£5,000|
|Sarah Howard||Southampton||Jessica Teeling||Investigating the role of neuroinflammation on the accumulation and spread of tau pathology||£4,908.16|
|Hanyi Jiang||Imperial||Javier Alegre Abarrategui||Development of assays for the direct visualization of early TDP43 protein aggregates in post-mortem tissue||£5,000|
|Elisavet Velentza-Almpani||Imperial||Javier Alegre Abarrategui||Spatiotemporal distribution and relationship to brain immunity of early tau aggregates||£5,000|
|Charlotte Dawson||Sheffield||Robin Highley||Clinical and pathological relationships in motor neurone disease||£5,000|
|Toomey / Lashley||UCL||Tammaryn Lashley||Targeting lipids as potential biomarkers in Alzheimer’s disease||£4,650|
|Olivia Jennings||Sheffield||Julie Simpson||Blood-brain barrier dysfunction the the ageing brain||£5,000|
|Connor Scott||Oxford||Olaf Ansorge||Investigating the transcriptome of the giant pyramidal Betz cell in human post-mortem brains||£5,000|
|Ketan Dipak Jetwa||Nottingham||Ian Scott||High-resolution structural and spectroscopic magnetic resonance imaging of the nucleus basalis in health and disease.||£4,000|
|Kirsty McAleese||Newcastle||Johannes Attems||The impact of concomitant TDP-43 pathology on tau pathology and cognitive decline in Alzheimer’s disease.||£4,795|
|Miles Frost||Southampton||Roxana Carare||The pattern of adrenergic innervation in human brains.||£5,000|
|Kastytis Sidlauskas||Southampton||Delphine Boche||Microglia/macrophage immunophenotypes in glioblastoma and their association with clinical outcome.||£5,000|
|Eleanor Schaber||Sheffield||Robin Highley||DNA hydroxymethylation in Amyotrophic Lateral Sclerosis, a pathological study into the role of 5-hydroxymethylcytosine and its related enzymes.||£3,500|
|Shivank Keni||Edinburgh||Colin Smith||A radiological, histological and molecular characterisation of the blood brain barrier in glioblastoma multiforme.||£5,000|
|Matthew Nolan||Oxford||Olaf Ansorge||Somatic mosaicism of the human ALS Brain.||£4,980|
|Rohith Srinivasan||Sheffield||Julie Simpson||Dysregulation of nitric oxide synthase (NOS) expression in the ageing brain||£5,000|
Postdoctoral small grants:
Athanasios Alexandris, Differential expression of galanin in the human cholinergic basal forebrain in Lewy body dementias, AD and dementia of mixed origin (AD/DLB)
Lida Zoupi, Grey Matter synaptopathy in MS: Synaptic profiles in damage and repair
Lindsey Sinclair, Are visual hallucinations in Alzheimer’s a result of decreased cholinergic input to visual processing areas of the brain?
Suvi Hokkanen, Genetic risk factors of the old-age hippocampal sclerosis, Cambridge
Julie Simpson, Neuronal Senescence as a Contributor to Neurodegeneration in Motor Neurone Disease, Sheffield
Difei Wang, e-Learning the molecular pathology of brain tumours, Royal London
Dr Yvonne Dombrowski (Dr Denise Fitzgerald), Queen’s University, Belfast. Identifying neuropathological mechanisms underlying paralysis following Treg depletion.
Dr Ashirwad Merve (Prof Silvia Marino), Blizard Institute, Barts and The London School of Medicine, London. Role of c-Myc in choroid plexus tumours.
Veronica Roberts: Is head shaking in horses, like trigeminal neuralgia in people, caused by trigeminal nerve root demyelination?
Claire Rice: Relevance of mitochondrial sirtuins to the pathogenesis of multiple sclerosis
Simon Paine: Novel co-regulated gene networks in epileptic cortex: insights into FCD and brain development
Harry Haynes, Frenchay Hospital, Bristol: Identification of EGFR/EGFRvIII mutations in glioblastoma multiforme as progonostic and predictive biomarkers
Owain Howell, University of Swansea/University of Cardiff: Development of a tissue microarray for biomarker discovery in multiple sclerosis